The 1st International Conference on Sustainable Intelligent Systems and Next-Gen Computing aims to provide a high-quality international forum for researchers, academicians, industry professionals, and innovators to present original and unpublished research addressing the design, development, and deployment of intelligent and next-generation computing systems with a strong emphasis on sustainability, security, and human-centricity. The conference covers theoretical foundations, algorithmic advances, system architectures, and real-world applications in areas such as artificial intelligence and machine learning, Internet of Things, blockchain technologies, cybersecurity, green and energy-efficient computing, Industry 5.0, smart cities, digital healthcare, and smart manufacturing. In addition to core research tracks, the conference features a dedicated Industry Track / Case Study Track that encourages applied research, industrial case studies, prototypes, deployment experiences, and solution-driven contributions from corporate R&D labs, startups, and technology practitioners. The conference also promotes industry partnerships and sponsorship-supported engagement through technical sessions, invited industry talks, and collaborative forums, fostering meaningful interaction between academia and industry.